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Search Results for " aryl hydrocarbon receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T7202 ITE AhR , Aryl Hydrocarbon Receptor
ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
T21966 MeBIO GSK-3 , Aryl Hydrocarbon Receptor , CDK
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.
T1960 YL-109 AhR , Aryl Hydrocarbon Receptor
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
TN1451 Brevifolincarboxylic acid AhR , Aryl Hydrocarbon Receptor , Glucosidase
Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 3...
T20625 Prochloraz Sporgon,Prelude Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal
Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and...
T4608 PDM2 AhR , Aryl Hydrocarbon Receptor
PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
T15410 GNF351 Aryl Hydrocarbon Receptor
GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes wit...
T2448 CH-223191 CH 223191 AhR , Aryl Hydrocarbon Receptor
CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
T5622 BAY-218 AHR antagonist 1 AhR , Aryl Hydrocarbon Receptor
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
T4607 CAY 10465 CAY10465,CAY10465 Exclusive AhR , Aryl Hydrocarbon Receptor
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
T10270 BAY 2416964 Aryl Hydrocarbon Receptor
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment.
T10007 1,4-Chrysenequinone Chrysene-1,4-dione AhR
1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).
TQ0257 FICZ 6-Formylindolo[3,2-b]carbazole Aryl Hydrocarbon Receptor
FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).
T6795 Carbidopa (S)-(-)-Carbidopa,Lodosyn Decarboxylase , Aryl Hydrocarbon Receptor
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.
T1831 StemRegenin 1 SR1 AhR , Aryl Hydrocarbon Receptor
StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.
T4928 L-Kynurenine (S)-Kynurenine AhR , Aryl Hydrocarbon Receptor , Endogenous Metabolite
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has ...
T0878 Diosmin Venosmine,Diosmil,Barosmin Aryl Hydrocarbon Receptor , Norepinephrine
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.
T21704 5-fluoro 203 5F-203,NSC-703786 Others
5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells...
T13276 VAF347 Aryl Hydrocarbon Receptor
VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.
T2623 PD98059 PD 98059 ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhibits autophagy.

Compounds

ITE
T7202
Synonym:
Target: AhR, Aryl Hydrocarbon Receptor
MeBIO
T21966
Synonym:
Target: GSK-3, Aryl Hydrocarbon Receptor, CDK
YL-109
T1960
Synonym:
Target: AhR, Aryl Hydrocarbon Receptor
Brevifolincarboxylic acid
TN1451
Synonym:
Target: AhR, Aryl Hydrocarbon Receptor, Glucosidase
Prochloraz
T20625
Synonym: Sporgon,Prelude
Target: Estrogen Receptor/ERR, AhR, Androgen Receptor, Antifungal
PDM2
T4608
Synonym:
Target: AhR, Aryl Hydrocarbon Receptor
GNF351
T15410
Synonym:
Target: Aryl Hydrocarbon Receptor
CH-223191
T2448
Synonym: CH 223191
Target: AhR, Aryl Hydrocarbon Receptor
BAY-218
T5622
Synonym: AHR antagonist 1
Target: AhR, Aryl Hydrocarbon Receptor
CAY 10465
T4607
Synonym: CAY10465,CAY10465 Exclusive
Target: AhR, Aryl Hydrocarbon Receptor
BAY 2416964
T10270
Synonym:
Target: Aryl Hydrocarbon Receptor
1,4-Chrysenequinone
T10007
Synonym: Chrysene-1,4-dione
Target: AhR
FICZ
TQ0257
Synonym: 6-Formylindolo[3,2-b]carbazole
Target: Aryl Hydrocarbon Receptor
Carbidopa
T6795
Synonym: (S)-(-)-Carbidopa,Lodosyn
Target: Decarboxylase, Aryl Hydrocarbon Receptor
StemRegenin 1
T1831
Synonym: SR1
Target: AhR, Aryl Hydrocarbon Receptor
L-Kynurenine
T4928
Synonym: (S)-Kynurenine
Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite
Diosmin
T0878
Synonym: Venosmine,Diosmil,Barosmin
Target: Aryl Hydrocarbon Receptor, Norepinephrine
5-fluoro 203
T21704
Synonym: 5F-203,NSC-703786
Target: Others
VAF347
T13276
Synonym:
Target: Aryl Hydrocarbon Receptor
PD98059
T2623
Synonym: PD 98059
Target: ERK, Aryl Hydrocarbon Receptor, MEK, Autophagy
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TargetMol